UCSF Endocrine Surgery and Oncology Program
Research Program & Clinical Trials
Dr. Kebebew studies the genetic and epigenetic abnormalities that are present in endocrine tumors. Understanding these changes that occur in endocrine cancer could help in developing strategies for early detection of endocrine cancers, and targets for therapy.
Current studies focus on:
- Identification and clinical validation of thyroid cancer biomarkers that could lead to early detection and better prognostication,
- Molecular classification and mechanism of dysregulated genes in malignant adrenal tumors,
- Novel therapeutic approaches to treat thyroid or adrenal cancer subpopulations that do not respond well to current conventional therapeutic strategies, and
- Molecular basis of gender and ethnic disparity in thyroid cancer incidence.
Translation research program in endocrine oncology
Active Clinical Trials
Entry criteria for the studies can be found through the links or is listed below.
- Rosiglitazone in Treating Patients With Locoregionally Extensive or Metastatic Thyroid Cancer
- Genetic Analysis in Diagnosing Thyroid Cancer in Patients With Thyroid Nodules
- Randomized Controlled Trial of Bipolar Versus Ultrasonic Hemostasis Techniques in Thyroidectomy
- Phase II Trial of Valproic Acid (Depakote ER) in Patients With Advanced Thyroid Cancer
- Thyroglobulin venous sampling study to detect residual and recurrent thyroid cancer.
Additional information on clinical trials currently under way at UCSF may be found at the UCSF Medical Center website and the UCSF Comprehensive Cancer Center.