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After completing medical school at the University of Iowa, I completed a residency in Anatomic Pathology at Wake Forest University Medical Center in Winston-Salem, NC. A love of dermatopathology ensued, and I began a dermatology residency and dermatopathology fellowship at UCSF, joining the faculty after completion of my training in 1991. My exclusive interest is the advancement of diagnostic dermatopathology. Our unit is particularly active as a bridge between conventional microscopy and molecular methods. In the realm of cutaneous lymphoma, we provide comprehensive consultation and classification, using both immunophenotyping and genotypic analysis (via both PCR and traditional Southern blot methods) as diagnostic supplements. We also provide consultative diagnoses for a large volume of melanocytic neoplasms, and a recent advance has been the clinical application of comparative genomic hybridization (CGH) to the evaluation of a broad spectrum of melanocytic neoplasms, including melanoma, Spitz's nevi, and cellular blue nevi, in collaboration with Dr. Boris Bastian. CGH permits assessment of genomic gains and deletions from paraffin-embedded material and should serve as the cornerstone for the diagnosis of difficult melanocytic lesions in the future. Additional areas of interest include the delineation of criteria for the microscopic diagnosis of inflammatory skin diseases and the classification and variation of cutaneous adnexal neoplasms. Selected References:
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links | research | staff | UCSF dermatology | UCSF pathology |
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